Results showed significant effects of PPT on outcome, of which Emotional Dysregulation demonstrated the largest association ( β = 0.43, p < 0.001). Baseline symptom level (BSI-pretreatment) was taken into account as a mediator or moderator variable. This study assessed the prognostic value of PPT (Dimensional Assessment of Personality Pathology–Short Form) on treatment outcome (Brief Symptom Inventory ) among patients with depressive and/or anxiety disorders ( N = 5689). Previous studies have failed to take baseline severity into account when assessing the effects of pathological personality traits (PPT) on treatment outcome. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s Web site ( This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Supplemental digital content is available for this article. All participants gave permission for the anonymized use of their data for research purposes. The research project was funded by the Dutch Mental Health Care Provider GGZ Rivierduinen.Įthical Considerations: The Medical Ethical Committee of the LUMC approved the general study protocol-with routine outcome monitoring being integral to the treatment process (no written informed consent was required). van Eeden, MSc, Leiden University Medical Centre, Department of Psychiatry, Albinusdreef 2, Postzone B1-P, 2300 RC Leiden, Zuid Holland, the Netherlands. †Clinical Psychology Unit, Institute of Psychology, Leiden University, Leiden, Zuid Holland, the Netherlands. ∗Department of Psychiatry, Leiden University Medical Centre (LUMC)
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